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Publications

A temperature-tolerant CRISPR base editor mediates highly efficient and precise gene editing in Drosophila.

Doll RM, Boutros M, Port F. Science Advances. 2023 Sep;9(35):eadj1568.

Summary: This paper describes a highly efficient base editor that can be used to install stop codons or generate protein variants with remarkable efficiency.

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila.

Port F, Strein C, Stricker M, Rauscher B, Heigwer F, Zhou J, Beyersdörffer C, Frei J, Hess A, Kern K, Lange L, Langner N, Malamud R, Pavlović B, Rädecke K, Schmitt L, Voos L, Valentini E, Boutros M. Elife. 2020 Feb 13;9:e53865.

Summary: Description and characterization of the HD-CFD library, a large-scale sgRNA collection of tissue-specific in vivo mutagenesis.

Systematic Evaluation of Drosophila CRISPR Tools Reveals Safe and Robust Alternatives to Autonomous Gene Drives in Basic Research.

Port F, Muschalik N, Bullock SL. G3 (Bethesda). 2015 May 20;5(7):1493-502.

Summary: Systemematic comparison of different CRISPR tools and protocols.